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Sirt2 Regulates Adipocyte Differentiation Involving FoxO1 Acetylation/Deacetylation
The mammalian Sirtuin proteins contain seven family members that are homologous to yeast Sir2. Here we show that Sirt2, a cytoplasmic sirtuin, is the most abundant sirtuin in adipocytes, its expression is down regulated during preadipocyte differentiation in 3T3-L1 cells. Over-expression of Sirt2 in...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2083635/ https://ncbi.nlm.nih.gov/pubmed/17681146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2007.07.003 |
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