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Sirt2 Regulates Adipocyte Differentiation Involving FoxO1 Acetylation/Deacetylation

The mammalian Sirtuin proteins contain seven family members that are homologous to yeast Sir2. Here we show that Sirt2, a cytoplasmic sirtuin, is the most abundant sirtuin in adipocytes, its expression is down regulated during preadipocyte differentiation in 3T3-L1 cells. Over-expression of Sirt2 in...

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Hlavní autoři: Jing, Enxuan, Gesta, Stephane, Ronald Kahn, C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2083635/
https://ncbi.nlm.nih.gov/pubmed/17681146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2007.07.003
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