Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs

Activation of Sirtuin1 (Sirt1), an nicotinamide adenine dinucleotide oxidized-dependent deacetylase, by natural or synthetic compounds like resveratrol, SRT2104, or SRT3025 attenuates the loss of bone mass caused by ovariectomy, aging, or unloading in mice. Conversely, Sirt1 deletion in osteoclast p...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Endocrinol
Main Authors: Kim, Ha-Neui, Han, Li, Iyer, Srividhya, de Cabo, Rafael, Zhao, Haibo, O'Brien, Charles A., Manolagas, Stavros C., Almeida, Maria
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2015
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588729/
https://ncbi.nlm.nih.gov/pubmed/26287518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1133
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki