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Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs
Activation of Sirtuin1 (Sirt1), an nicotinamide adenine dinucleotide oxidized-dependent deacetylase, by natural or synthetic compounds like resveratrol, SRT2104, or SRT3025 attenuates the loss of bone mass caused by ovariectomy, aging, or unloading in mice. Conversely, Sirt1 deletion in osteoclast p...
Shranjeno v:
| izdano v: | Mol Endocrinol |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Endocrine Society
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4588729/ https://ncbi.nlm.nih.gov/pubmed/26287518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1133 |
| Oznake: |
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