Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs

Activation of Sirtuin1 (Sirt1), an nicotinamide adenine dinucleotide oxidized-dependent deacetylase, by natural or synthetic compounds like resveratrol, SRT2104, or SRT3025 attenuates the loss of bone mass caused by ovariectomy, aging, or unloading in mice. Conversely, Sirt1 deletion in osteoclast p...

詳細記述

保存先:
書誌詳細
出版年:Mol Endocrinol
主要な著者: Kim, Ha-Neui, Han, Li, Iyer, Srividhya, de Cabo, Rafael, Zhao, Haibo, O'Brien, Charles A., Manolagas, Stavros C., Almeida, Maria
フォーマット: Artigo
言語:Inglês
出版事項: Endocrine Society 2015
主題:
Original Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588729/
https://ncbi.nlm.nih.gov/pubmed/26287518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1133
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