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Hepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6

Cholesterol homeostasis is crucial for cellular function and organismal health. The key regulator for the cholesterol biosynthesis is sterol-regulatory element binding protein (SREBP)-2. The biochemical process and physiological function of SREBP-2 have been well characterized; however, it is not cl...

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Autores principales: Tao, Rongya, Xiong, Xiwen, DePinho, Ronald A., Deng, Chu-Xia, Dong, X. Charlie
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770087/
https://ncbi.nlm.nih.gov/pubmed/23881913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M039339
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