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Feedback regulation of hepatic gluconeogenesis through modulation of SHP/Nr0b2 gene expression by Sirt1 and FoxO1

Protein deacetylase Sirt1 has been implicated in the regulation of hepatic gluconeogenesis; however, the mechanisms are not fully understood. To further elucidate how Sirt1 regulates gluconeogenesis, we took a loss-of-function approach by deleting the coding DNA sequence for the catalytic domain of...

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Detalhes bibliográficos
Main Authors: Wei, Dan, Tao, Rongya, Zhang, Yao, White, Morris F., Dong, X. Charlie
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043623/
https://ncbi.nlm.nih.gov/pubmed/21081708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00524.2010
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