Mouse Sirt3 promotes autophagy in AngII-induced myocardial hypertrophy through the deacetylation of FoxO1

Sirt3, a mitochondrial NAD+-dependent histone deacetylase, is the only member proven to promote longevity in mammalian Sirtuin family. The processed short form of Sirt3 has been demonstrated to target many mediators of energy metabolism and mitochondrial stress adaptive program. Autophagy serves as...

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Vydáno v:Oncotarget
Hlavní autoři: Li, Jingyuan, Chen, Tongshuai, Xiao, Ming, Li, Na, Wang, Shujian, Su, Hongyan, Guo, Xiaobin, Liu, Hui, Yan, Fangying, Yang, Yi, Zhang, Yun, Bu, Peili
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349942/
https://ncbi.nlm.nih.gov/pubmed/27880725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13429
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