Mouse Sirt3 promotes autophagy in AngII-induced myocardial hypertrophy through the deacetylation of FoxO1

Sirt3, a mitochondrial NAD+-dependent histone deacetylase, is the only member proven to promote longevity in mammalian Sirtuin family. The processed short form of Sirt3 has been demonstrated to target many mediators of energy metabolism and mitochondrial stress adaptive program. Autophagy serves as...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Li, Jingyuan, Chen, Tongshuai, Xiao, Ming, Li, Na, Wang, Shujian, Su, Hongyan, Guo, Xiaobin, Liu, Hui, Yan, Fangying, Yang, Yi, Zhang, Yun, Bu, Peili
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349942/
https://ncbi.nlm.nih.gov/pubmed/27880725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13429
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