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Mouse SIRT3 Attenuates Hypertrophy-Related Lipid Accumulation in the Heart through the Deacetylation of LCAD

Cardiac hypertrophy is an adaptive response to pressure, volume stress, and loss of contractile mass from prior infarction. Metabolic changes in cardiac hypertrophy include suppression of fatty acid oxidation and enhancement of glucose utilization, which could result in lipid accumulation in the hea...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chen, Tongshuai, Liu, Junni, Li, Na, Wang, Shujian, Liu, Hui, Li, Jingyuan, Zhang, Yun, Bu, Peili
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351969/
https://ncbi.nlm.nih.gov/pubmed/25748450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118909
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