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FoxO1 Mediates PTEN Suppression of Androgen Receptor N- and C-Terminal Interactions and Coactivator Recruitment

FoxO (mammalian forkhead subclass O) proteins are transcription factors acting downstream of the PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor. Their activity is negatively regulated by AKT-mediated phosphorylation. Our previous studies showed that the transcription...

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Bibliografische gegevens
Hoofdauteurs: Ma, Qiuping, Fu, Wei, Li, Pengfei, Nicosia, Santo V., Jenster, Guido, Zhang, Xiaohong, Bai, Wenlong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Endocrine Society 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646622/
https://ncbi.nlm.nih.gov/pubmed/19074551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0147
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