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FoxO1 Mediates PTEN Suppression of Androgen Receptor N- and C-Terminal Interactions and Coactivator Recruitment

FoxO (mammalian forkhead subclass O) proteins are transcription factors acting downstream of the PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor. Their activity is negatively regulated by AKT-mediated phosphorylation. Our previous studies showed that the transcription...

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Detalhes bibliográficos
Main Authors: Ma, Qiuping, Fu, Wei, Li, Pengfei, Nicosia, Santo V., Jenster, Guido, Zhang, Xiaohong, Bai, Wenlong
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646622/
https://ncbi.nlm.nih.gov/pubmed/19074551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0147
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