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FoxO3 suppresses Myc-driven lymphomagenesis
This study demonstrates, for the first time, that loss of a single forkhead box class O (FoxO) transcription factor, can promote lymphomagenesis. Using two different mouse models, we show that FoxO3 has a significant tumour-suppressor function in the context of Myc-driven lymphomagenesis. Loss of Fo...
Shranjeno v:
| izdano v: | Cell Death Dis |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4816178/ https://ncbi.nlm.nih.gov/pubmed/26764572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.396 |
| Oznake: |
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