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FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf
FoxO transcription factors play critical roles in cell cycle control and cellular stress responses, and abrogation of FoxO function promotes focus formation by Myc in vitro. Here we show that stable introduction of a dominant-negative FoxO moiety (dnFoxO) into Eμ-myc transgenic hematopoietic stem ce...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2045131/ https://ncbi.nlm.nih.gov/pubmed/17974917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.453107 |
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