FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf

FoxO transcription factors play critical roles in cell cycle control and cellular stress responses, and abrogation of FoxO function promotes focus formation by Myc in vitro. Here we show that stable introduction of a dominant-negative FoxO moiety (dnFoxO) into Eμ-myc transgenic hematopoietic stem ce...

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Autors principals: Bouchard, Caroline, Lee, Soyoung, Paulus-Hock, Viola, Loddenkemper, Christoph, Eilers, Martin, Schmitt, Clemens A.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2007
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045131/
https://ncbi.nlm.nih.gov/pubmed/17974917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.453107
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