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Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation
Forkhead box class O (FOXO) proteins are transcription factors that function downstream of the PTEN tumor suppressor and directly control the expression of genes involved in apoptosis, cell cycle progression, and stress responses. In the present study, we show that FOXO1 interacts with four and a ha...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC554122/ https://ncbi.nlm.nih.gov/pubmed/15692560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600570 |
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