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Characterization of Protein Z-Dependent Protease Inhibitor/Antithrombin Chimeras Provides Insight into the Serpin Specificity of Coagulation Proteases

[Image: see text] Protein Z (PZ)-dependent protease inhibitor (ZPI) and antithrombin (AT) are two physiological serpin inhibitors involved in the regulation of proteolytic activities of the blood coagulation cascade. ZPI has restricted protease specificity capable of inhibiting factors Xa (FXa) and...

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Библиографические подробности
Опубликовано в: :ACS Omega
Главные авторы: Yang, Likui, Rezaie, Alireza R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2017
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537704/
https://ncbi.nlm.nih.gov/pubmed/28782047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00606
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