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Characterization of the Protein Z-dependent Protease Inhibitor Interactive-sites of Protein Z

BACKGROUND: Protein Z (PZ) has been reported to promote the inactivation of factor Xa (FXa) by PZ-dependent protease inhibitor (ZPI) three orders of magnitude. Previously, we prepared a chimeric PZ in which its C-terminal pseudo-catalytic domain was grafted on FX light-chain (Gla and EGF-like domain...

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Detalhes bibliográficos
Main Authors: Qureshi, Shabir H, Lu, Qiuya, Manithody, Chandrashekhara, Yang, Likui, Rezaie, Alireza R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118583/
https://ncbi.nlm.nih.gov/pubmed/24960590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2014.06.011
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