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Protein Z-dependent Protease Inhibitor Binds to the C-terminal Domain of Protein Z

Protein Z (PZ) is a multidomain vitamin K-dependent plasma protein that functions as a cofactor to promote the inactivation of factor Xa (fXa) by PZ-dependent protease inhibitor (ZPI) by three orders of magnitude. To understand the mechanism by which PZ improves the reactivity of fXa with ZPI, we ex...

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Detalhes bibliográficos
Main Authors: Rezaie, Alireza R., Bae, Jong-Sup, Manithody, Chandrashekhara, Qureshi, Shabir H., Yang, Likui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2459281/
https://ncbi.nlm.nih.gov/pubmed/18502758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802639200
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