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Autolysis loop restricts the specificity of activated protein C: Analysis by FRET and functional assays
We previously demonstrated that the substitution of the autolysis loop (residues 143-154 in chymotrypsin numbering) of APC with the corresponding loop of trypsin (APC-Tryp(143-154)) has no influence on the proteolytic activity of the protease toward fVa, however, this substitution increases the reac...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2387052/ https://ncbi.nlm.nih.gov/pubmed/18329782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2008.02.012 |
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