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The functional significance of the autolysis loop in protein C and activated protein C
The autolysis loop of activated protein C (APC) is five residues longer than the autolysis loop of other vitamin K-dependent coagulation proteases. To investigate the role of this loop in the zymogenic and anticoagulant properties of the molecule, a protein C mutant was constructed in which the auto...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1193704/ https://ncbi.nlm.nih.gov/pubmed/16113785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1267/THRO05010060 |
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