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Characterization of Protein Z-Dependent Protease Inhibitor/Antithrombin Chimeras Provides Insight into the Serpin Specificity of Coagulation Proteases

[Image: see text] Protein Z (PZ)-dependent protease inhibitor (ZPI) and antithrombin (AT) are two physiological serpin inhibitors involved in the regulation of proteolytic activities of the blood coagulation cascade. ZPI has restricted protease specificity capable of inhibiting factors Xa (FXa) and...

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Bibliografiske detaljer
Udgivet i:ACS Omega
Main Authors: Yang, Likui, Rezaie, Alireza R.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2017
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537704/
https://ncbi.nlm.nih.gov/pubmed/28782047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00606
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