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Characterization of Protein Z-Dependent Protease Inhibitor/Antithrombin Chimeras Provides Insight into the Serpin Specificity of Coagulation Proteases

[Image: see text] Protein Z (PZ)-dependent protease inhibitor (ZPI) and antithrombin (AT) are two physiological serpin inhibitors involved in the regulation of proteolytic activities of the blood coagulation cascade. ZPI has restricted protease specificity capable of inhibiting factors Xa (FXa) and...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Yang, Likui, Rezaie, Alireza R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537704/
https://ncbi.nlm.nih.gov/pubmed/28782047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00606
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