Prion strains depend on different endocytic routes for productive infection

Prions are unconventional agents composed of misfolded prion protein that cause fatal neurodegenerative diseases in mammals. Prion strains induce specific neuropathological changes in selected brain areas. The mechanism of strain-specific cell tropism is unknown. We hypothesised that prion strains r...

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Publicado en:Sci Rep
Main Authors: Fehlinger, Andrea, Wolf, Hanna, Hossinger, André, Duernberger, Yvonne, Pleschka, Catharina, Riemschoss, Katrin, Liu, Shu, Bester, Romina, Paulsen, Lydia, Priola, Suzette A., Groschup, Martin H., Schätzl, Hermann M., Vorberg, Ina M.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537368/
https://ncbi.nlm.nih.gov/pubmed/28761068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07260-2
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