Modulation of Glycosaminoglycans Affects PrP(Sc) Metabolism but Does Not Block PrP(Sc) Uptake

Mammalian prions are unconventional infectious agents composed primarily of the misfolded aggregated host prion protein PrP, termed PrP(Sc). Prions propagate by the recruitment and conformational conversion of cellular prion protein into abnormal prion aggregates on the cell surface or along the end...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Wolf, Hanna, Graßmann, Andrea, Bester, Romina, Hossinger, André, Möhl, Christoph, Paulsen, Lydia, Groschup, Martin H., Schätzl, Hermann, Vorberg, Ina
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Prions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577896/
https://ncbi.nlm.nih.gov/pubmed/26202247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01276-15
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