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Modulation of Glycosaminoglycans Affects PrP(Sc) Metabolism but Does Not Block PrP(Sc) Uptake
Mammalian prions are unconventional infectious agents composed primarily of the misfolded aggregated host prion protein PrP, termed PrP(Sc). Prions propagate by the recruitment and conformational conversion of cellular prion protein into abnormal prion aggregates on the cell surface or along the end...
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| Veröffentlicht in: | J Virol |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4577896/ https://ncbi.nlm.nih.gov/pubmed/26202247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01276-15 |
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