Modulation of Glycosaminoglycans Affects PrP(Sc) Metabolism but Does Not Block PrP(Sc) Uptake

Mammalian prions are unconventional infectious agents composed primarily of the misfolded aggregated host prion protein PrP, termed PrP(Sc). Prions propagate by the recruitment and conformational conversion of cellular prion protein into abnormal prion aggregates on the cell surface or along the end...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Wolf, Hanna, Graßmann, Andrea, Bester, Romina, Hossinger, André, Möhl, Christoph, Paulsen, Lydia, Groschup, Martin H., Schätzl, Hermann, Vorberg, Ina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2015
Gaiak:
Prions
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577896/
https://ncbi.nlm.nih.gov/pubmed/26202247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01276-15
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