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Modulation of Glycosaminoglycans Affects PrP(Sc) Metabolism but Does Not Block PrP(Sc) Uptake

Mammalian prions are unconventional infectious agents composed primarily of the misfolded aggregated host prion protein PrP, termed PrP(Sc). Prions propagate by the recruitment and conformational conversion of cellular prion protein into abnormal prion aggregates on the cell surface or along the end...

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Foilsithe in:J Virol
Main Authors: Wolf, Hanna, Graßmann, Andrea, Bester, Romina, Hossinger, André, Möhl, Christoph, Paulsen, Lydia, Groschup, Martin H., Schätzl, Hermann, Vorberg, Ina
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577896/
https://ncbi.nlm.nih.gov/pubmed/26202247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01276-15
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