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Multiple Amino Acid Residues within the Rabbit Prion Protein Inhibit Formation of Its Abnormal Isoform

Transmissible spongiform encephalopathies (TSEs) are neurological diseases that are associated with the conversion of the normal host-encoded prion protein (PrP-sen) to an abnormal protease-resistant form, PrP-res. Transmission of the TSE agent from one species to another is usually inefficient and...

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Detalhes bibliográficos
Main Authors: Vorberg, Ina, Groschup, Martin H., Pfaff, Eberhard, Priola, Suzette A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140934/
https://ncbi.nlm.nih.gov/pubmed/12525634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.3.2003-2009.2003
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