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Efficient Conversion of Normal Prion Protein (PrP) by Abnormal Hamster PrP Is Determined by Homology at Amino Acid Residue 155

In the transmissible spongiform encephalopathies, disease is closely associated with the conversion of the normal proteinase K-sensitive host prion protein (PrP-sen) to the abnormal proteinase K-resistant form (PrP-res). Amino acid sequence homology between PrP-res and PrP-sen is important in the fo...

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Udgivet i:J Virol
Principais autores: Priola, Suzette A., Chabry, Joëlle, Chan, Kaman
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114221/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11312338/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.10.4673-4680.2001
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