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Efficient Conversion of Normal Prion Protein (PrP) by Abnormal Hamster PrP Is Determined by Homology at Amino Acid Residue 155

In the transmissible spongiform encephalopathies, disease is closely associated with the conversion of the normal proteinase K-sensitive host prion protein (PrP-sen) to the abnormal proteinase K-resistant form (PrP-res). Amino acid sequence homology between PrP-res and PrP-sen is important in the fo...

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Autors principals: Priola, Suzette A., Chabry, Joëlle, Chan, Kaman
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC114221/
https://ncbi.nlm.nih.gov/pubmed/11312338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.10.4673-4680.2001
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