Heterologous PrP molecules interfere with accumulation of protease-resistant PrP in scrapie-infected murine neuroblastoma cells.

Mutations within a host cellular protein, PrP, have been associated with disease in the transmissible spongiform encephalopathies. Murine neuroblastoma cells persistently infected with mouse scrapie accumulate protease-resistant PrP (PrP-res), the abnormal form of PrP associated with disease in the...

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Bibliographic Details
Published in:J Virol
Main Authors: Priola, S A, Caughey, B, Race, R E, Chesebro, B
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236427/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7913509/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.8.4873-4878.1994
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