PrP Expression and Replication by Schwann Cells: Implications in Prion Spreading

Prion infection relies on a continuous chain of PrP(c)-expressing tissues to spread from peripheral sites to the central nervous system (CNS). Direct neuroinvasion via peripheral nerves has long been considered likely. However, the speed of axonal flow is incompatible with the lengthy delay prior to...

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Detalhes bibliográficos
Main Authors: Follet, Jérôme, Lemaire-Vieille, Catherine, Blanquet-Grossard, Françoise, Podevin-Dimster, Valérie, Lehmann, Sylvain, Chauvin, Jean-Paul, Decavel, Jean-Pierre, Varea, Ruth, Grassi, Jacques, Fontès, Michel, Cesbron, Jean-Yves
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135945/
https://ncbi.nlm.nih.gov/pubmed/11836421
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