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Prion protein (PrP) gene-knockout cell lines: insight into functions of the PrP

Elucidation of prion protein (PrP) functions is crucial to fully understand prion diseases. A major approach to studying PrP functions is the use of PrP gene-knockout (Prnp-/-) mice. So far, six types of Prnp-/- mice have been generated, demonstrating the promiscuous functions of PrP. Recently, othe...

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Bibliografiske detaljer
Principais autores: Akikazu eSakudo, Takashi eOnodera
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015-01-01
Serier:Frontiers in Cell and Developmental Biology
Fag:
Online adgang:http://journal.frontiersin.org/Journal/10.3389/fcell.2014.00075/full
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