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Prion Replication in the Mammalian Cytosol: Functional Regions within a Prion Domain Driving Induction, Propagation, and Inheritance

Prions of lower eukaryotes are transmissible protein particles that propagate by converting homotypic soluble proteins into growing protein assemblies. Prion activity is conferred by so-called prion domains, regions of low complexity that are often enriched in glutamines and asparagines (Q/N). The c...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Duernberger, Yvonne, Liu, Shu, Riemschoss, Katrin, Paulsen, Lydia, Bester, Romina, Kuhn, Peer-Hendrik, Schölling, Manuel, Lichtenthaler, Stefan F., Vorberg, Ina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048315/
https://ncbi.nlm.nih.gov/pubmed/29784771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00111-18
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