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Cell-to-cell propagation of infectious cytosolic protein aggregates

Prions are self-templating protein conformers that replicate by recruitment and conversion of homotypic proteins into growing protein aggregates. Originally identified as causative agents of transmissible spongiform encephalopathies, increasing evidence now suggests that prion-like phenomena are mor...

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Detalhes bibliográficos
Main Authors: Hofmann, Julia P., Denner, Philip, Nussbaum-Krammer, Carmen, Kuhn, Peer-Hendrik, Suhre, Michael H., Scheibel, Thomas, Lichtenthaler, Stefan F., Schätzl, Hermann M., Bano, Daniele, Vorberg, Ina M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625284/
https://ncbi.nlm.nih.gov/pubmed/23509289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217321110
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