Hyperglycemia exacerbates colon cancer malignancy through hexosamine biosynthetic pathway

Hyperglycemia is a common feature of diabetes mellitus, considered as a risk factor for cancer. However, its direct effects in cancer cell behavior are relatively unexplored. Herein we show that high glucose concentration induces aberrant glycosylation, increased cell proliferation, invasion and tum...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncogenesis
Prif Awduron: Vasconcelos-dos-Santos, A, Loponte, H F B R, Mantuano, N R, Oliveira, I A, de Paula, I F, Teixeira, L K, de-Freitas-Junior, J C M, Gondim, K C, Heise, N, Mohana-Borges, R, Morgado-Díaz, J A, Dias, W B, Todeschini, A R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533945/
https://ncbi.nlm.nih.gov/pubmed/28319096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.2
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