Hyperglycemia exacerbates colon cancer malignancy through hexosamine biosynthetic pathway

Hyperglycemia is a common feature of diabetes mellitus, considered as a risk factor for cancer. However, its direct effects in cancer cell behavior are relatively unexplored. Herein we show that high glucose concentration induces aberrant glycosylation, increased cell proliferation, invasion and tum...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Vasconcelos-dos-Santos, A, Loponte, H F B R, Mantuano, N R, Oliveira, I A, de Paula, I F, Teixeira, L K, de-Freitas-Junior, J C M, Gondim, K C, Heise, N, Mohana-Borges, R, Morgado-Díaz, J A, Dias, W B, Todeschini, A R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533945/
https://ncbi.nlm.nih.gov/pubmed/28319096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.2
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