Hyperglycemia exacerbates colon cancer malignancy through hexosamine biosynthetic pathway

Hyperglycemia is a common feature of diabetes mellitus, considered as a risk factor for cancer. However, its direct effects in cancer cell behavior are relatively unexplored. Herein we show that high glucose concentration induces aberrant glycosylation, increased cell proliferation, invasion and tum...

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Bibliografiske detaljer
Udgivet i:Oncogenesis
Main Authors: Vasconcelos-dos-Santos, A, Loponte, H F B R, Mantuano, N R, Oliveira, I A, de Paula, I F, Teixeira, L K, de-Freitas-Junior, J C M, Gondim, K C, Heise, N, Mohana-Borges, R, Morgado-Díaz, J A, Dias, W B, Todeschini, A R
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533945/
https://ncbi.nlm.nih.gov/pubmed/28319096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.2
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