Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila

We explore the hypothesis that pathology of Huntington's disease involves multiple cellular mechanisms whose contributions to disease are incrementally additive or synergistic. We provide evidence that the photoreceptor neuron degeneration seen in flies expressing mutant human huntingtin correl...

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Autores principales: Agrawal, Namita, Pallos, Judit, Slepko, Natalia, Apostol, Barbara L., Bodai, Laszlo, Chang, Ling-Wen, Chiang, Ann-Shyn, Thompson, Leslie Michels, Marsh, J. Lawrence
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2005
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC553288/
https://ncbi.nlm.nih.gov/pubmed/15716359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500055102
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