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Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila

We explore the hypothesis that pathology of Huntington's disease involves multiple cellular mechanisms whose contributions to disease are incrementally additive or synergistic. We provide evidence that the photoreceptor neuron degeneration seen in flies expressing mutant human huntingtin correl...

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Détails bibliographiques
Auteurs principaux: Agrawal, Namita, Pallos, Judit, Slepko, Natalia, Apostol, Barbara L., Bodai, Laszlo, Chang, Ling-Wen, Chiang, Ann-Shyn, Thompson, Leslie Michels, Marsh, J. Lawrence
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC553288/
https://ncbi.nlm.nih.gov/pubmed/15716359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500055102
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