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A novel target for Huntington’s disease: ERK at the crossroads of signaling: The ERK signaling pathway is implicated in Huntington’s disease and its upregulation ameliorates pathology

Activating the ERK pathway (extracellular signal-regulated kinase pathway) has proven beneficial in several models of Huntington’s disease, and drugs that are protective in HD models have recently been found to activate ERK. Thus, the ERK cascade may be a potential target for therapeutic interventio...

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Bibliografski detalji
Glavni autori: Bodai, László, Marsh, J. Lawrence
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711381/
https://ncbi.nlm.nih.gov/pubmed/22334892
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