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A novel target for Huntington’s disease: ERK at the crossroads of signaling: The ERK signaling pathway is implicated in Huntington’s disease and its upregulation ameliorates pathology

Activating the ERK pathway (extracellular signal-regulated kinase pathway) has proven beneficial in several models of Huntington’s disease, and drugs that are protective in HD models have recently been found to activate ERK. Thus, the ERK cascade may be a potential target for therapeutic interventio...

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Détails bibliographiques
Auteurs principaux: Bodai, László, Marsh, J. Lawrence
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711381/
https://ncbi.nlm.nih.gov/pubmed/22334892
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