Gene co-expression networks identify Trem2 and Tyrobp as major hubs in human APOE expressing mice following traumatic brain injury

Traumatic brain injury (TBI) is strongly linked to an increased risk of developing dementia, including chronic traumatic encephalopathy and possibly Alzheimer’s disease (AD). APOEε4 allele of human Apolipoprotein E (APOE) gene is the major genetic risk factor for late onset AD and has been associate...

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Veröffentlicht in:Neurobiol Dis
Hauptverfasser: Castranio, Emilie L., Mounier, Anais, Wolfe, Cody M., Nam, Kyong Nyon, Fitz, Nicholas F., Letronne, Florent, Schug, Jonathan, Koldamova, Radosveta, Lefterov, Iliya
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530876/
https://ncbi.nlm.nih.gov/pubmed/28502803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.05.006
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