Integrated approach reveals diet, APOE genotype and sex affect immune response in APP mice

Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder that is influenced by genetic and environmental risk factors, such as inheritance of ε4 allele of APOE (APOE4), sex and diet. Here, we examined the effect of high fat diet (HFD) on amyloid pathology and expression profile in bra...

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Gepubliceerd in:Biochim Biophys Acta
Hoofdauteurs: Nam, Kyong Nyon, Wolfe, Cody M., Fitz, Nicholas F., Letronne, Florent, Castranio, Emilie L., Mounier, Anais, Schug, Jonathan, Lefterov, Iliya, Koldamova, Radosveta
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714325/
https://ncbi.nlm.nih.gov/pubmed/29038051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.10.018
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