Gene co-expression networks identify Trem2 and Tyrobp as major hubs in human APOE expressing mice following traumatic brain injury

Traumatic brain injury (TBI) is strongly linked to an increased risk of developing dementia, including chronic traumatic encephalopathy and possibly Alzheimer’s disease (AD). APOEε4 allele of human Apolipoprotein E (APOE) gene is the major genetic risk factor for late onset AD and has been associate...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neurobiol Dis
Prif Awduron: Castranio, Emilie L., Mounier, Anais, Wolfe, Cody M., Nam, Kyong Nyon, Fitz, Nicholas F., Letronne, Florent, Schug, Jonathan, Koldamova, Radosveta, Lefterov, Iliya
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530876/
https://ncbi.nlm.nih.gov/pubmed/28502803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.05.006
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