Gene co-expression networks identify Trem2 and Tyrobp as major hubs in human APOE expressing mice following traumatic brain injury

Traumatic brain injury (TBI) is strongly linked to an increased risk of developing dementia, including chronic traumatic encephalopathy and possibly Alzheimer’s disease (AD). APOEε4 allele of human Apolipoprotein E (APOE) gene is the major genetic risk factor for late onset AD and has been associate...

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Publicado no:Neurobiol Dis
Main Authors: Castranio, Emilie L., Mounier, Anais, Wolfe, Cody M., Nam, Kyong Nyon, Fitz, Nicholas F., Letronne, Florent, Schug, Jonathan, Koldamova, Radosveta, Lefterov, Iliya
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530876/
https://ncbi.nlm.nih.gov/pubmed/28502803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.05.006
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