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The Role of APOE and TREM2 in Alzheimer′s Disease—Current Understanding and Perspectives
Alzheimer’s disease (AD) is the leading cause of dementia worldwide. The extracellular deposits of Amyloid beta (Aβ) in the brain—called amyloid plaques, and neurofibrillary tangles—intracellular tau aggregates, are morphological hallmarks of the disease. The risk for AD is a complicated interplay b...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6337314/ https://ncbi.nlm.nih.gov/pubmed/30587772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20010081 |
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