The Role of APOE and TREM2 in Alzheimer′s Disease—Current Understanding and Perspectives

Alzheimer’s disease (AD) is the leading cause of dementia worldwide. The extracellular deposits of Amyloid beta (Aβ) in the brain—called amyloid plaques, and neurofibrillary tangles—intracellular tau aggregates, are morphological hallmarks of the disease. The risk for AD is a complicated interplay b...

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Sparad:
Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Wolfe, Cody M., Fitz, Nicholas F., Nam, Kyong Nyon, Lefterov, Iliya, Koldamova, Radosveta
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2018
Ämnen:
Review
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337314/
https://ncbi.nlm.nih.gov/pubmed/30587772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20010081
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