Efficacy of Rhesus Theta-Defensin-1 in Experimental Models of Pseudomonas aeruginosa Lung Infection and Inflammation

Chronic airway infection and inflammation contribute to the progressive loss of lung function and shortened survival of patients with cystic fibrosis (CF). Rhesus theta defensin-1 (RTD-1) is a macrocyclic host defense peptide with antimicrobial and immunomodulatory activities. Combined with favorabl...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Bensman, Timothy J., Jayne, Jordanna G., Sun, Meiling, Kimura, Elza, Meinert, Joshua, Wang, Joshua C., Schaal, Justin B., Tran, Dat, Rao, Adupa P., Akbari, Omid, Selsted, Michael E., Beringer, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527632/
https://ncbi.nlm.nih.gov/pubmed/28559270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00154-17
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