Rhesus θ-Defensin-1 Attenuates Endotoxin-induced Acute Lung Injury by Inhibiting Proinflammatory Cytokines and Neutrophil Recruitment

Acute lung injury (ALI) is a clinical syndrome characterized by acute respiratory failure and is associated with substantial morbidity and mortality. Rhesus θ-defensin (RTD)-1 is an antimicrobial peptide with immunomodulatory activity. As airway inflammation and neutrophil recruitment and activation...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Jayne, Jordanna G., Bensman, Timothy J., Schaal, Justin B., Park, A. Young J., Kimura, Elza, Tran, Dat, Selsted, Michael E., Beringer, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854954/
https://ncbi.nlm.nih.gov/pubmed/28954201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0428OC
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