Efficacy of Rhesus Theta-Defensin-1 in Experimental Models of Pseudomonas aeruginosa Lung Infection and Inflammation

Chronic airway infection and inflammation contribute to the progressive loss of lung function and shortened survival of patients with cystic fibrosis (CF). Rhesus theta defensin-1 (RTD-1) is a macrocyclic host defense peptide with antimicrobial and immunomodulatory activities. Combined with favorabl...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Bensman, Timothy J., Jayne, Jordanna G., Sun, Meiling, Kimura, Elza, Meinert, Joshua, Wang, Joshua C., Schaal, Justin B., Tran, Dat, Rao, Adupa P., Akbari, Omid, Selsted, Michael E., Beringer, Paul M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527632/
https://ncbi.nlm.nih.gov/pubmed/28559270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00154-17
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