Efficacy of Rhesus Theta-Defensin-1 in Experimental Models of Pseudomonas aeruginosa Lung Infection and Inflammation

Chronic airway infection and inflammation contribute to the progressive loss of lung function and shortened survival of patients with cystic fibrosis (CF). Rhesus theta defensin-1 (RTD-1) is a macrocyclic host defense peptide with antimicrobial and immunomodulatory activities. Combined with favorabl...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Bensman, Timothy J., Jayne, Jordanna G., Sun, Meiling, Kimura, Elza, Meinert, Joshua, Wang, Joshua C., Schaal, Justin B., Tran, Dat, Rao, Adupa P., Akbari, Omid, Selsted, Michael E., Beringer, Paul M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527632/
https://ncbi.nlm.nih.gov/pubmed/28559270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00154-17
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