Microbicidal Properties and Cytocidal Selectivity of Rhesus Macaque Theta Defensins

Rhesus macaque θ-defensins (RTDs) are unique macrocyclic antimicrobial peptides. The three RTDs (RTD 1-3), isolated from macaque leukocytes, have broad-spectrum antimicrobial activities in vitro and share certain structural features with acyclic porcine protegrins, which are microbicidal peptides of...

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Bibliografiske detaljer
Main Authors: Tran, Dat, Tran, Patti, Roberts, Kevin, Ösapay, George, Schaal, Justin, Ouellette, Andre, Selsted, Michael E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258523/
https://ncbi.nlm.nih.gov/pubmed/18160518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01090-07
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