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Rhesus macaque θ‐defensin RTD‐1 inhibits proinflammatory cytokine secretion and gene expression by inhibiting the activation of NF‐κB and MAPK pathways
θ‐Defensins are pleiotropic, macrocyclic peptides that are expressed uniquely in Old World monkeys. The peptides are potent, broad‐spectrum microbicides that also modulate inflammatory responses in vitro and in animal models of viral infection and polymicrobial sepsis. θ‐Defensins suppress proinflam...
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| Publicado no: | J Leukoc Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4661038/ https://ncbi.nlm.nih.gov/pubmed/26269197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0315-102R |
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