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Rhesus macaque θ-defensin isoforms: expression, antimicrobial activities, and demonstration of a prominent role in neutrophil granule microbicidal activities

Mammalian defensins are cationic, antimicrobial peptides that play a central role in innate immunity. The peptides are composed of three structural subfamilies: α-, β-, and θ-defensins. θ-Defensins are macrocyclic octadecapeptides expressed only in Old World monkeys and Orangutans and are produced b...

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Detalhes bibliográficos
Main Authors: Tongaonkar, Prasad, Tran, Patti, Roberts, Kevin, Schaal, Justin, Ösapay, George, Tran, Dat, Ouellette, André J., Selsted, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024902/
https://ncbi.nlm.nih.gov/pubmed/21084627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0910535
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