Curative Treatment of Severe Gram-Negative Bacterial Infections by a New Class of Antibiotics Targeting LpxC

The infectious diseases caused by multidrug-resistant bacteria pose serious threats to humankind. It has been suggested that an antibiotic targeting LpxC of the lipid A biosynthetic pathway in Gram-negative bacteria is a promising strategy for curing Gram-negative bacterial infections. However, expe...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Lemaître, Nadine, Liang, Xiaofei, Najeeb, Javaria, Lee, Chul-Jin, Titecat, Marie, Leteurtre, Emmanuelle, Simonet, Michel, Toone, Eric J., Zhou, Pei, Sebbane, Florent
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527309/
https://ncbi.nlm.nih.gov/pubmed/28743813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00674-17
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