Загрузка...
Synthesis, structure and antibiotic activity of aryl-substituted LpxC inhibitors
The zinc-dependent deacetylase LpxC catalyzes the committed step of lipid A biosynthesis in Gram-negative bacteria and is a validated target for development of novel antibiotics to combat multidrug-resistant Gram-negative infections. Many potent LpxC inhibitors contain an essential threonyl-hydroxam...
Сохранить в:
| Главные авторы: | , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3941642/ https://ncbi.nlm.nih.gov/pubmed/23914798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm4007774 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|