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Apolipoprotein E as a Therapeutic Target in Alzheimer’s disease: A Review of Basic Research and Clinical Evidence

Alzheimer’s disease (AD) is a devastating neurodegenerative disorder which causes progressive cognitive decline. The majority of AD cases are sporadic and late-onset (> 65 years old) making it the leading cause of dementia in the elderly. While both genetic and environmental factors contribute to...

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Detalhes bibliográficos
Publicado no:CNS Drugs
Main Authors: Yamazaki, Yu, Painter, Meghan M., Bu, Guojun, Kanekiyo, Takahisa
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526196/
https://ncbi.nlm.nih.gov/pubmed/27328687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40263-016-0361-4
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