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Apolipoprotein E as a Therapeutic Target in Alzheimer’s disease: A Review of Basic Research and Clinical Evidence

Alzheimer’s disease (AD) is a devastating neurodegenerative disorder which causes progressive cognitive decline. The majority of AD cases are sporadic and late-onset (> 65 years old) making it the leading cause of dementia in the elderly. While both genetic and environmental factors contribute to...

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Vydáno v:CNS Drugs
Hlavní autoři: Yamazaki, Yu, Painter, Meghan M., Bu, Guojun, Kanekiyo, Takahisa
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526196/
https://ncbi.nlm.nih.gov/pubmed/27328687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40263-016-0361-4
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