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Apolipoprotein E and Alzheimer disease: risk, mechanisms, and therapy
Apolipoprotein E (ApoE) is a major cholesterol carrier that supports lipid transport and injury repair in the brain. APOE polymorphic alleles are the main genetic determinants of Alzheimer disease (AD) risk: individuals carrying the ε4 allele are at increased risk of AD compared with those carrying...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726719/ https://ncbi.nlm.nih.gov/pubmed/23296339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneurol.2012.263 |
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