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Apolipoprotein E and its receptors in Alzheimer’s disease: pathways, pathogenesis and therapy
The vast majority of Alzheimer’s disease (AD) cases are late-onset and their development is likely influenced by both genetic and environmental risk factors. A strong genetic risk factor for late-onset AD is the presence of the ε4 allele of the apolipoprotein E (APOE) gene, which encodes a protein w...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2908393/ https://ncbi.nlm.nih.gov/pubmed/19339974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrn2620 |
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