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Apolipoprotein E and its receptors in Alzheimer’s disease: pathways, pathogenesis and therapy

The vast majority of Alzheimer’s disease (AD) cases are late-onset and their development is likely influenced by both genetic and environmental risk factors. A strong genetic risk factor for late-onset AD is the presence of the ε4 allele of the apolipoprotein E (APOE) gene, which encodes a protein w...

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Hlavní autor: Bu, Guojun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908393/
https://ncbi.nlm.nih.gov/pubmed/19339974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrn2620
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