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Titratable Avidity Reduction Enhances Affinity Discrimination in Mammalian Cellular Selections of Yeast-Displayed Ligands
Yeast surface display selections against mammalian cell monolayers have proven effective in isolating proteins with novel binding activity. Recent advances in this technique allow for recovery of clones with even micromolar binding affinity. However, no efficient method has been shown for affinity b...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | ACS Comb Sci |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5521271/ https://ncbi.nlm.nih.gov/pubmed/28322543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscombsci.6b00191 |
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